23 Jul Functional nano-crystalline cellulose hydrogel and preparation method thereof
Abstract
The invention relates to functional nano-crystalline cellulose hydrogel and a preparation method thereof. The interior of the hydrogel is of a uniform porous mesh structure, and the pore size of the hydrogel is 30-100 microns. The hydrogel is prepared by the following steps: dispersing TEMPO oxidized cellulose in water to prepare nano-cellulose dispersion, mixing with cells to prepare bio-ink, andprinting into an ionic crosslinking agent by utilizing a 3D bio-printing technology, thereby obtaining the product. The shape of the product can be designed according to needs. The renewable resourcecellulose serves as a raw material, and the functional nano-crystalline cellulose hydrogel with advantages of being excellent in mechanical property, excellent in biocompatibility and applicable to bio-printing is prepared. The prepared hydrogel serves as a nano-cellulose based tissue engineering material, is particularly one of tissues such as bones, cartilage, skin, blood vessels, liver, heartand the like, the application range of the cellulose is widened, and a novel pathway is provided for application research of the cellulose in the biomedical field.
Year: 2019
Country: CN
Doc No: 109180988