Fiber-reinforced injectable bone tissue engineering stent material adopting in-situ solidification and pore formation and preparation method thereof

Fiber-reinforced injectable bone tissue engineering stent material adopting in-situ solidification and pore formation and preparation method thereof

Abstract

The invention belongs to the field of medical materials and particularly relates to a fiber-reinforced injectable bone tissue engineering stent material adopting in-situ solidification and pore formation and a preparation method thereof. The injectable bone tissue engineering stent material comprises polylactide-glycolide, hydroxyapatite, polyglycollide fibers and an organic solvent, wherein the ratio of the total mass of the polylactide-glycolide, the hydroxyapatite and the polyglycollide fibers to the volume of the organic solvent is (5-10)g:(10-50)mL. The injectable bone tissue engineering stent material has the advantages that the polylactide-glycolide, the hydroxyapatite and the polyglycollide fibers are used as the solute components of the injectable bone tissue engineering stent material, and the mechanical strength of the material after injection solidification is increased evidently; experiment results show that the compressive strength of the solidified injectable bone tissue engineering stent material is not smaller than 15MPa, and the elasticity modulus of the solidified injectable bone tissue engineering stent material is not smaller than 15MPa.

Year:  2017

Country:  CN

Doc No:  107050506

 

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