23 Jul Extracellular polymeric substances, preparation method and application thereof
Abstract
The invention discloses extracellular polymeric substances, a preparation method and an application thereof. The extracellular polysaccharide is obtained by fermented extraction of engineered strain bacillus subtilis (a preservation number is CCTCC M 2016074), the preparation method is characterized in that the engineered strain bacillus subtilis is constructed by a gene engineering technology, then is subjected to fermentation, extraction and purification to obtain the uniform extracellular polysaccharide. The monosaccharide of the extracellular polysaccharide is composed of mannose, glucose, fucose, galactose and glucuronic acid, and molecular weight is about 450 million Dalton. A hydrodynamic research analysis displays that the polysaccharide is pseudoplastic fluid; and a histocompatibility research analysis displays that the polysaccharide has good histocompatibility. The extracellular polysaccharide can be used in tissue filling restoration, tissue engineering support materials, drug-loaded support materials, and wound dressing.
Year: 2017
Country: CN
Doc No: 106381279