23 Jul ENZYMATIC METHOD FOR PRODUCING BIOACTIVE, OSTEOBLAST-STIMULATING SURFACES AND USE THEREOF
Posted at 13:56h
in rest
Abstract
The invention relates to a method for producing bioactive surfaces by enzymatic modification of molecules or molecular aggregates, in particular, collagen, on surfaces of glass, metals, metallic oxides, plastics, biopolymers or other materials with an amorphous silicon dioxide (silica) or silicones in the cell culture, by tissue engineering or in medical implants, whereby a polypeptide is used for enzymatic modification, which contains a silicatein alpha or silicatein beta domain. The inventive method promotes the growth, activity and/or mineralisation of cells/cell cultures.
Year: 2005
Country: WO
Doc No: 2005106004