23 Jul Enhanced silk fibroin artificial jaw scaffold and preparation method thereof
Abstract
The invention discloses an enhanced silk fibroin artificial jaw scaffold. The enhanced silk fibroin artificial jaw scaffold is prepared from the components in percentage by weight: 88-96% of decalcified dentin granules, 3-9% of silk fibroin and 1-3% of PEG. The enhanced silk fibroin artificial jaw scaffold can be used in bone tissue engineering, cells are combined with scaffold materials, the defects of bone source shortage, many postoperative complications, poor biocompatibility of materials and the like are overcome, so that the face of a patient is restored well and the operation cost is reduced; the domestic silkworm silk fibroin, decalcified cementum and PEG are reasonably compounded, the obtained composite scaffold has high mechanical properties, moderate degradation rate in vivo, directional osteogenic differentiation ability, no acid degradation products, and immune rejection is reduced.
Year: 2019
Country: CN
Doc No: 110420354