23 Jul Electrostatic spinning tissue engineering blood vessel receiving device having nonlinear mechanical performance
Abstract
The invention provides an electrostatic spinning tissue engineering blood vessel receiving device having nonlinear mechanical performance and solves the problem of low performance matchability between grown tissue engineering blood vessels and real blood vessels. The receiving device comprises a propeller which is connected with a spinning nozzle, an electrostatic high-voltage applying device is arranged at the spinning nozzle, and a collection device is arranged at the spinning nozzle and comprises a rotating shaft and a moving shaft moving back and forth in a horizontal plane. In the prior art, stress strain curve of tissue engineering blood vessels prepared by electrostatic spinning technology has a gap with needs of the real blood vessels, and a main reason is that the tissue engineering blood vessels have no low-stress large-strain areas. By improving the receiving device to enable collected fiber to be bent by a certain degree, prepared blood vessels are enabled to realize areas I at the early stage of deformation by straightening bent portions of the fiber, and blood vessels can expand greatly under small stress to adapt to the circumstance of momentary blood flow increase.
Year: 2017
Country: CN
Doc No: 107201557