23 Jul Elastic gel support material for bone tissue engineering and preparation method of material
Abstract
The invention discloses an elastic gel support material for bone tissue engineering and a preparation method of the material. The material consists of a gel N1 and a gel N2, wherein the molar content of the gel N1 is 5-50% and the molar content of the gel N2 is 50-95%. The preparation method comprises the following steps: fully dissolving a gel N1 reaction monomer, a gel N1 crosslinking agent and a gel N1 accelerant in deionized water to obtain a gel N1 synthesized solution; introducing N2 to remove oxygen in the solution, and adding a free radical initiator to initiate polymerization of the free radical to obtain the gel N1; fully dissolving a gel N2 reaction monomer, a gel N2 crosslinking agent and a photoinitiator in deionized water to obtain a gel N2 synthesized solution; and adding the gel N1 into the gel N2 synthesized solution to be fully immersed, and then irradiating and photo-initiating polymerization of the free radical under an ultraviolet lamp to obtain a double-network gel. The component of gel in the material is cytoactive, can adapt in vivo dynamic environment and can be applied to bone tissue repair materials.
Year: 2014
Country: CN
Doc No: 103920184