23 Jul Elastic double-layer tubular tissue engineering scaffold with multistage porous structure and preparation method thereof
Abstract
The invention relates to an elastic double-layer tubular tissue engineering scaffold with a multistage porous structure and a preparation method thereof. The tissue engineering scaffold includes nanofibers and a tubular spring scaffold which is prepared through 4-axis 3D printing. The nano fibers coat the surface of the scaffold to form the double-layer structure. The multistage porous structureincludes the pores formed by interlacing the linear materials in the tubular spring scaffold, micro-pores or nano-pores, which are uniformly distributed in the linear materials and are communicated with each other, and nano-porous structures, which are formed by depositing, wrapping and interlacing the nano fibers. The invention solves the essential problem that FDM is difficult to directly use for printing a porous tubular scaffold. The tissue engineering scaffold has the accurately-controllable multistage porous structure. The method is simple and quick, is suitable for various biomaterialsand has excellent application prospect.
Year: 2019
Country: CN
Doc No: 109529122