23 Jul Double network structure macromolecule hydrogel preparation method based on full physical cross-linking
Abstract
The invention discloses a double network structure macromolecule hydrogel preparation method based on full physical cross-linking. According to the preparation method, a large number of the hydroxyl groups and the amide groups in a macromolecule polymer easily form hydrogen bonds, RDS sol type laponite can be used as the physical cross-linking point of a polyacrylamide network, a nanometer laponite/polyacrylamide first network is prepared through free radical polymerization, and the first network is subjected to physical cross-linking with polyvinyl alcohol through a freezing/thawing circulation method to obtain a second network, such that the polyvinyl alcohol/polyacrylamide-laponite full physical cross-linking double network hydrogel is synthesized through the two-step method. Accordingto the present invention, the method has advantages of simple operation, easy control, mild preparation condition, time and space controllability, time and space selectivity, good repeatability, environmental protection, simple equipment, low cost and the like, and has broad application prospects in the fields of drug delivery and controlled release, tissue engineering, bio-bionic, artificial muscles, biosensors and the like.
Year: 2019
Country: CN
Doc No: 110183581