23 Jul Double-network hydrogel based on PEG (polyethylene glycol) and polysaccharides as well as preparation method and application of double-network hydrogel
Abstract
The invention discloses a double-network hydrogel based on PEG (polyethylene glycol) and polysaccharides as well as a preparation method and an application of the double-network hydrogel. The chemical-physical/chemical double-network hydrogel is formed under the hydrogen bond interaction between a first chemical network and a second physical/chemical network; the first chemical network is formed by a chemical reaction of a PEG derivative 1 and a PEG derivative 2; the second physical/chemical network is formed by either crosslinking of polysaccharides or derivatives thereof or by interaction between the polysaccharides or derivatives thereof and a crosslinking agent. The high-strength chemical-physical/chemical double-network hydrogel with good self-recovery capability and good biocompatibility has potential application in the following fields: drug sustained-release materials, tissue engineering scaffolds, medical sponge, medical implants and surface coatings of the medical implants.
Year: 2017
Country: CN
Doc No: 106519264