Dissolving and spraying preparation method of mechanical property optimized silk fibroin biological scaffold for tissue engineering

Dissolving and spraying preparation method of mechanical property optimized silk fibroin biological scaffold for tissue engineering

Abstract

The technical scheme discloses a dissolving and spraying preparation method of a mechanical property optimized silk fibroin biological scaffold for tissue engineering, the preparation method comprisesthe step of post-processing of fiber spinning, the specific process is as follows: the fiber spinning is sprayed through an ethyl alcohol spraying device, wherein the spraying speed of ethyl alcoholin the ethyl alcohol spraying device is 100-1000 mL/min, and the bioprotein scaffold for tissue engineering is prepared. The silk fibroin spinning fiber is processed in the technical scheme to promotethe transformation of random conformation in the silk fibroin to beta folded conformation, so that the macroscopic even-texture silk fibroin biological scaffold for tissue engineering is obtained; the silk fibroin biological scaffold for tissue engineering prepared in the technical scheme can be applied to scaffolds for tissue engineering for blood vessels, urethras, cartilages and bones, and canalso be used to filter blood after surface treatment.

Year:  2019

Country:  CN

Doc No:  109610020

 

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