23 Jul DEVICE AND METHODS FOR PRINTING BIOLOGICAL TISSUES AND ORGANS
Abstract
The invention relates to medicine and biology, and specifically to means for artificially creating biological tissues and organs, and may be used in biotechnology, bioengineering, tissue engineering, regenerative medicine, and in the 3-D printing of biological tissues and organs. The essence of the invention consists in developing a method for printing biological tissues and organs, and in a device for implementing same. The proposed device contains, at least: a platform for printing; a bio-ink printing module containing at least one nozzle capable of dosing bio-inks; a gel-forming-composition printing module, containing a UV-module, and at least one nozzle capable of dosing a gel-forming composition which polymerizes under the influence of UV radiation; and a module for relatively displacing nozzles and/or the platform; and in which the bio-ink printing module is separated from the gel-forming-composition printing module in such a way so as to prevent UV radiation from reaching the bio-ink printing module, the radiation from the UV module being directed predominantly parallel to the platform for printing, in such a way so as to prevent UV radiation from reaching the biological tissues and/or organs being printed. The technical result consists in creating a multi-functional device capable of combining various printing modes, in allowing for the high-resolution printing of biological tissues and organs on the basis of a high-resolution hydrogel which polymerizes under the effect of UV radiation, and also in protecting cells from ultraviolet (UV) radiation during printing.
Year: 2016
Country: WO
Doc No: 2016036275