23 Jul Degradable three-dimensional porous magnesium-based biomaterial and preparation method thereof
Abstract
The invention discloses a degradable three-dimensional porous magnesium-based biomaterial and a preparation method thereof. The porous magnesium and magnesium alloy materials are in a three-dimensional through complete opening structure; the hole pattern is a sphere with a controllable dimension; intercommunicating holes are uniform in distribution and controllable in dimension; and a magnesium fluoride film is uniformly generated on the surface of each hole wall. The holes of the material obtained by the method are uniform in overall distribution; the porosity and the mechanical property are controllable; titanium sphere or iron sphere particles are sintered in preparation, so as to obtain a porous preform with spherical openings; magnesium and magnesium alloy infiltrate into the preform and then are cooled to room temperature; and the preform is removed through hydrofluoric acid solution corrosion. The preparation method is simple in preparation technology and convenient to operate; an anti-corrosion anti-fouling membrane is formed on a magnesium and magnesium alloy matrix surface in the removal process of the preform; the magnesium-based biomaterial is good in connectivity, and relatively high in porosity and strength; the hole wall is free of corrosion or pore-forming agent residue phenomenon; a closed hole does not exist; and the magnesium-based biomaterial can be used as a new generation of degradable tissue engineering scaffold.
Year: 2015
Country: CN
Doc No: 104689368