23 Jul Degradable magnesium-containing calcium phosphate-calcium sulfate porous composite biological scaffold
Abstract
The invention discloses a degradable magnesium-containing calcium phosphate-calcium sulfate porous composite biological scaffold which is prepared by the following steps: treating a bovine calcined cancellous bone mineral porous scaffold by a magnesium-source/sulfur-source/phosphorus-source-containing ternary system, taking out, drying, and carrying out high-temperature calcination. The degradable magnesium-containing calcium phosphate-calcium sulfate porous composite biological scaffold has a favorable three-dimensional intercommunication mesh structure, and has favorable osteoconductivity, degradability, mechanical strength and biocompatibility. The high-length-diameter-ratio calcium sulfate whiskers growing in the meshes can increase the specific area of the material, thereby possibly improving the cell adhesion. By effectively doping the osteogenesis active ionic magnesium and the calcium sulfate capable of generating a partial high-calcium environment during degradation, the composite biological scaffold can have the potential bone inductivity. The composite biological scaffold can satisfy the ideal conditions for bone transplantation alternate materials or bone tissue engineering scaffold materials.
Year: 2017
Country: CN
Doc No: 106310381