23 Jul Degradable blood vessel casting agent
Abstract
The invention relates to a degradable blood vessel casting agent. The casting agent consists of casting material and an organic solvent. 1ml of the casting agent contains 0.05 to 0.5g of the casting material. The casting material is one of polylactic acid, polyglycollic acid and polycaprolactone or the combination of any two; and the organic solvent is acetone, ethyl acetate, chloroform or 1,4-dioxane. The preparation and application process of the casting agent is simple and easily operated. The concentration of the casting agent is timely regulated as required; and the casting agent can be used for feeding a cast many times during casting so as to maintain the natural form of a blood vessel maximally. After being injected into the blood vessel or a blood vessel die, the casting agent can be completely solidified through a plurality of drying methods; and then a blood vessel cast is obtained after the corrosive removal of tissues and cleaning or after opening the blood vessel die. The blood vessel cast prepared from the casting agent has certain toughness and mechanical strength. The casting agent has good biocompatibility, easy molding, and easy percolation and dissolution, and is suitable for the study on the preparation of a hepatic tissue engineering support with a physiological shape blood vessel network.
Year: 2009
Country: CN
Doc No: 101544814