23 Jul Construction of human hepatocyte growth factor gene recomginant retroviral vector
Abstract
The present invention relates to field of biological medicine, in the concrete, it relates to the creation of recombinant retroviral vector carrying human hepatocytegrowth factor (HGF) gene. Said invention provides a recombinant retroviral vector carrying human hepatocytegrowth factor gene, and creates the packaging cell strain PT-HGF capable of high-titre producing human hepatocytegrowth factor retroviral granules so as to attain the goal of high-effectively stably expressing human hepatocytegrowth factor gene and giving full play to its biological functions of accelerating cell division, morphosis, motion, vascularization and resisting death. The creation of said recombinant retroviral vector possesses good application prospect in the regeneration medicine using gene engineering, stem cell engineering and tissue engineering as basis.
Year: 2004
Country: CN
Doc No: 1536085