Construction of controlled-release TrkC receptor ligand gelatin sponge cylinder bracket for repairing spinal cord injury

Construction of controlled-release TrkC receptor ligand gelatin sponge cylinder bracket for repairing spinal cord injury

Abstract

The invention relates to a construction method of a controlled-release TrkC receptor ligand-NT-3 (neurotrophin-3) gelatin sponge cylinder bracket for repairing the spinal cord injury, particularly to a construction method of a controlled-release TrkC receptor ligand gelatin sponge bracket material containing overexpression TrkC receptor cells. During application, the controlled-release TrkC receptor ligand gelatin sponge cylinder bracket with the overexpression TrkC receptor cells and differentiated cells of the overexpression TrkC receptor cells implanted is transplanted to a cross-sectional spinal cord injury position and can better promote regeneration and function repair of injured nervous centralis. The construction method has great significance in enhancement of protection of injured nerve cells after the cross-sectional spinal cord injury at the biological tissue engineering level, promotion of axonal regeneration of the nerve cells, improvement on the quality of life of the sick and the injured, reduction of social and family burdens and promotion of social and economic development in China.

Year:  2015

Country:  CN

Doc No:  104258460

 

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