Construction method of in-vitro GBM invasion model based on biological three-dimensional printing

Construction method of in-vitro GBM invasion model based on biological three-dimensional printing

Abstract

The invention discloses a construction method of an in-vitro glioblastoma (GBM) invasion model based on biological three-dimensional printing, which belongs to the field of tissue engineering and biological three-dimensional (3D) printing. According to the method, hydrogel containing cells is used as biological ink, and an in-vitro GBM invasion model is constructed by using a biological three-dimensional printer. The model structure is formed by printing hydrogel carrying normal human brain glial cells, and is inoculated with glioma cell clusters. The model has important significance for researching invasive growth of GBM, and is expected to provide help for researching a treatment method of polymorphic glioblastoma.

Year:  2019

Country:  CN

Doc No:  110564690

 

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