23 Jul Construction method of bioactive surface of tooth
Abstract
The invention discloses a construction method of a bioactive surface of the tooth. The construction method is characterized in that a three-dimensional pore layer composed of a titanium oxide bracketand apatite is constructed on the surface of pure titanium by utilizing the sand blasting technology and the micro-arc oxidation-electrophoresis technology, then the growth factors, namely, fibronectin (Fn) and bone morphogenetic protein (BMP) relevant to the bone growth and development and regeneration are selected, according to the conception of the tissue engineering biological scaffold, the growth factors, namely, fibronectin (Fn) and bone morphogenetic protein (BMP) have deposition with bioactive molecules having chemical adsorption on the surface of the titanium oxidation layer and are fixed in the microenvironment of the three-dimensional pore layer, thus the surface of the implant can induce and regulate osteogenesis and participate in bone matrix material interchange, then the construction and self-repairing capacity needed by the long-term harmonious coexistence with the body is available, and the physical-chemical-biological synosteosis participated by the tooth and the bone tissue is formed. With the method, the synosteosis time of the tooth can be greatly shortened, the capacity and success rate for long-term harmonious coexistence of the tooth in the body are improved, and the vital signs of the artificial organs are realized to a certain degree.
Year: 2019
Country: CN
Doc No: 109276756