23 Jul Construction for tissue engineering cartilage modified by transforming growth factor beta2 gene
Abstract
The present invention discloses process of constructing transforming growth factor beta2 gene modified tissue engineering cartilage. The process includes the separation, culturing and proliferation of adult stem cell from human fat, the transfection of type 5 copying defect adenovirus to the adult stem cell from human fat, the compound of the transfected cell and the polyhydroxy acetic acid/calcium alginate composite as the carrier material, and the formation of in vivo tissue engineering cartilage. Experiment shows that it is possible to form in vivo tissue engineering cartilage through inoculating adult stem cell from human fat to the polyhydroxy acetic acid/calcium alginate composite, and this shows the application foreground of gene reinforced tissue engineering in repairing cartilage defect.
Year: 2008
Country: CN
Doc No: 101148657