23 Jul Compound three-dimensional tissue engineering scaffold and preparation method thereof
Abstract
The invention discloses a compound three-dimensional tissue engineering scaffold which is characterized by being prepared by compounding a fibrous membrane I, a fibrous membrane II and a porous membrane arranged between the fibrous membrane I and the fibrous membrane II; both the fibrous membrane I and the fibrous membrane II are prepared by arranging hydrophilic PHB (poly-beta-hydroxybutyrate) fiber bundles; the porous membrane is a PHB porous membrane, a PLLA (poly-L-lactide) porous membrane or a PHB/PLLA compound porous membrane. The compound three-dimensional tissue engineering scaffold disclosed by the invention has good tissue compatibility and remarkable degradation degree, meanwhile, fiber structures in the scaffold can be used for increasing attached space of cells and preventing losing of superficial implanted cells; the degradation rate of the compound three-dimensional tissue engineering scaffold is adaptable to the requirements of growth rate of cells, and the structure and the performance of the scaffold are completely suitable for spreading, adhesion, growth and multiplication of cells, so that the compound three-dimensional tissue engineering scaffold provides a good micro environment for growth of cells.
Year: 2012
Country: CN
Doc No: 102580155