23 Jul Composite tissue engineering scaffold material with anti-infection property and manufacturing method thereof
Abstract
The invention relates to a composite tissue engineering scaffold material with anti-infection property and a manufacturing method thereof, in particular to a tissue engineering scaffold material. The invention provides the composite tissue engineering scaffold material with the anti-infection property and the manufacturing method thereof. The composite tissue engineering scaffold material is antibiotic microsphere-gelatin-oxosilane three-dimensional porous tissue engineering scaffold material which is formed by compounding the antibiotic microsphere, the gelatin, 3-(2,3-glycidoxypropyl) propyl trimethoxysilane and calcium salt. The freeze-dried antibiotic microsphere is dispersed into acid solution and then added with the gelatin solution to be dissolved to obtain solution A; the solution A is added with the calcium salt to obtain solution B, and GPSM is added into the solution B to be mixed together to obtain solution C; the solution C is injected into a mould, and microsphere-gelatin-oxosilane gel can be obtained by sol-gel; ammonia water solution is injected into the mould filled with the microsphere-gelatin-oxosilane gel for soaking gel, demoulding and washing; and the microsphere-gelatin-oxosilane gel is treated by freezing-freeze-drying method, and the product can be obtained after freeze-drying.
Year: 2010
Country: CN
Doc No: 101698115