23 Jul Composite stent material
Abstract
The invention relates to the technical field of tissue engineering, and in particular relates to a composite stent material. A preparation method of the composite stent material comprises the steps that a chitosan solution is mixed with an I-type collagen solution; pH is kept acidic; a chitosan /I-type collagen compound is obtained, mixed with a cross-linking agent, and subjected to freeze drying; a multi-hole stent is obtained, and soaked in a serum-free medium; the serum-free medium is removed; a dental pulp stem cell suspension liquid is added; standing is performed; a complete medium is added for cell culture; and the composite stent material is obtained. The research of composite stent material shows that a dental pulp stem cell has better osteogenic differentiation capacity than a bone marrow stem cell; and the dental pulp stem cell can be tightly combined with the stent material, grows well in the stent material well, and can be applied to treatment on a bone defect better.
Year: 2015
Country: CN
Doc No: 104707176