23 Jul Composite stent material preparation method, product and application method thereof
Abstract
The invention discloses a composite stent material preparation method and a product and an application method thereof. The method includes mixing silk fibroin powder with polyvinyl alcohol powder anddistilled water, conducting repeated freezing on the mixture and then fully mixing the mixture with hydroxyapatite powder and then conducting freeze drying. The preparation method is simple in processstep and convenient to operate. A freeze drying physical method is reasonably matched to prepare the material, and the mechanical problem like brittleness of the single material is solved. The secondary conformation of the composite stent material is changed, the mechanical performance of the composite stent material and the water solution stability are improved, no chemical reagent is added in the whole process, and no toxic or side effects are generated. The composite stent material has high forming precision, good mechanical property, controllable degradation rate and stable drug release rate. A prepared three-dimensional porous structure stent has good pore penetration, meets the requirements of the drug-loading tissue engineering bone stent material for the porous structure, and is favorable for wide-scale promotion.
Year: 2019
Country: CN
Doc No: 109821065