Composite porous fibers with core-shell structures and preparation method of dual-pore structure membrane

Composite porous fibers with core-shell structures and preparation method of dual-pore structure membrane

Abstract

The invention discloses a preparation method of high-conductivity hollow porous composite fibers which take a conductive polymer as a shell and a degradable polymer as a core and have core-shell structures, and a dual-pore structure membrane of the high-conductivity hollow porous composite fibers as well as an application of the dual-pore structure membrane in tissue engineering. The preparation method comprises the steps of preparing the degradable polymer, hollow fibers with porous surfaces and the dual-pore structure membrane through an electrostatic spinning method, preparing a degradable polymer/conductive high polymer, hollow porous composite fibers and a dual-pore structure membrane thereof through an in-situ polymerization method, and cleaning and drying to obtain the high-conductivity hollow porous composite fibers with the core-shell structures and the dual-pore structure membrane of the high-conductivity hollow porous composite fibers. The high-conductivity composite micron/nano-fiber dual-pore structure membrane prepared by the invention can be applied to nerve tissue engineering, has the advantages of high conductivity, high porosity, large pore size and good chemical stability, and has a practical value in nerve tissue engineering, and the preparation method of the membrane is simple and feasible.

Year:  2014

Country:  CN

Doc No:  103572606

 

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