23 Jul Chitosan-based self-healing gel and preparation method thereof
Abstract
The invention discloses chitosan-based self-healing gel and a preparation method of the chitosan-based self-healing gel. The preparation method comprises the following steps: putting chitosan in a mixed solvent of KOH, LiOH, NaOH, urea and thiourea, thus obtaining a chitosan solution through a freezing-defreezing process; adding acrylamide in the chitosan solution, thus preparing acrylamide chitosan; oxidizing by sodium periodate, thus preparing oxidized natural polysaccharide; mixing the acrylamide chitosan with the oxidized natural polysaccharide according to a certain proportion, thus preparing a gel material, wherein self repairing on damage after gel is damaged can be realized. According to the preparation method disclosed by the invention, the chitosan gel with good self-healing performance, good biocompatibility and good biodegradability can be obtained, and a wide application prospect in many fields of biomedical materials, tissue engineering, medical packaging materials and the like is obtained.
Year: 2016
Country: CN
Doc No: 105968390