23 Jul Cell transplantation culture method for forming bone tissue in vivo
Abstract
The invention relates to a cell transplantation culture method for forming bone tissue in vivo. The method is characterized in that a three-dimensional matrix BD Matrigel with fast degradation performance is employed to provide a three-dimensional structure for osteogenous seed cells to grow in vivo, so that an osteoid tissue structure can form in osteogenous seed cells. At the same time, BD Matrigel has certain dissolving capacity, corresponding growth factors or small molecular compounds and the like can be added at the early stage of cell transplantation so as to provide a microenvironment suitable for cell differentiation and survival at the early stage of in-vivo growth of the transplanted cells. The method provided by the invention can also be used for transplantation of various cells in tissue engineering, brings convenience to basic research, and brings prospects for clinical application.
Year: 2015
Country: CN
Doc No: 105169484