23 Jul Cardiac muscle tonifying tablet taking acellular biological membrane as carrier as well as preparation method and application of cardiac muscle tonifying tablet
Abstract
The invention discloses a cardiac muscle tonifying tablet taking an acellular biological membrane as a carrier as well as a preparation method and application of the cardiac muscle tonifying tablet. The cardiac muscle tonifying tablet taking the acellular biological membrane as the carrier is prepared by the following steps: carrying out decellularizing treatment on a natural biological membrane; then, cross-linking nutrient substances on the acellular biological membrane; planting target cells on the acellular biological membrane cross-linked with the nutrient substances; and cultivating a cell sheet which is preliminarily constructed, so that the cardiac muscle tonifying tablet taking the acellular biological membrane as the carrier is prepared. The cardiac muscle tonifying tablet disclosed by the invention is good in proliferation and differentiation activities and mechanical strength, and is sufficient in nutrition support; the cardiac muscle tonifying tablet is not only a breakthrough in tissue engineering but also suitable for the clinical treatment of myocardial infarction. The cardiac muscle tonifying tablet disclosed by the invention is reliable in principle, good in reproducibility, and suitable for standard production.
Year: 2015
Country: CN
Doc No: 104436305