23 Jul Bone tissue engineering bracket material and preparation method thereof
Abstract
The invention discloses a bone tissue engineering bracket material and a preparation method thereof. The method comprises the following steps: mixing polyactic acid-glycolic acid copolymer copolymer solution, dimethylsulfone solution and hydroxyapatite suspension to obtain mixed suspension; and freeze-drying the mixed suspension to obtain the bone tissue engineering bracket material. Compared with the prior art, the method has the advantages that the dimethylsulfone (MSM) with bioactivity is introduced, so the biocompatibility and the bioactivity of the bracket are improved; and a freeze-drying technology is adopted, so loss of the dimethylsulfone is effectively avoided, the release time of the dimethylsulfone is prolonged and the therapeutic effect time is prolonged. The dimethylsulfone has the characteristics of low price and easy availability, has high stability and dissolubility in solvents such as acetone and the like and is suitable for clinical application and popularization. The test result shows that the prepared bone tissue engineering bracket material has high biocompatibility and bioactivity.
Year: 2012
Country: CN
Doc No: 102552984