23 Jul Bionic composite scaffold material doped with graphene and establishment method of bionic composite support material
Abstract
The invention belongs to the field of tissue engineering scaffold materials, and provides a bionic composite scaffold material doped with graphene and an establishment method of the bionic composite support material. The establishment method comprises the following steps: firstly preparing a Cs acetic acid solution, a GP aqueous solution, a Gel aqueous solution and a graphene suspension, and thenmixing the Cs acetic acid solution and the GP aqueous solution to prepare a Cs/GP solution A; adding the Gel aqueous solution into the Cs/GP solution A to prepare a Cs/GP/Gel solution B; and adding the graphene suspension into the Cs/GP/Gel solution B to prepare a Cs/GP/Gel/Gr solution C, transferring the solution C into a low-temperature mold, freeze drying at a low temperature, and performing the subsequent treatment, thus obtaining the bionic cartilage composite support material. A mass ratio of chitosan Cs to beta-sodium glycerophosphate GP to gelatin Gel to graphene Gr in the bionic cartilage composite scaffold material is 1: (5 to 20): (1 to 5): (0.02 to 0.08). The bionic composite scaffold material has the advantages of simple process, easy control and low production cost; and a produced support product is uniform in porosity, has an inter-connective pore structure and has an excellent bionic effect.
Year: 2018
Country: CN
Doc No: 108273139