23 Jul Bionic bone tissue engineering bracket as well as preparation method and application thereof
Abstract
The invention discloses a bionic bone tissue engineering bracket as well as a preparation method and application thereof. The method comprises the following steps: firstly, performing carboxylation and dopamine surface modification on carbon nano tubes (CNTs) in turn; forming hydroxyapatite grains on the dopamine CNTs surfaces under the condition of simulated body fluid, thereby constructing biological mineralized CNTs; utilizing agarose to construct a main body bracket and utilizing an electrophoretic technique to move the mineralized CNTs in the bracket and form an array in parallel in sequence, thereby constructing the bionic bone tissue engineering bracket AG-o-CNTs. The bionic bone tissue engineering bracket AG-o-CNTs disclosed by the invention can effectively promote the growth of mesenchymal stem cells (bMSCs) and has wide application prospect at the aspect of bone tissue engineering bracket material or bone substitute material.
Year: 2017
Country: CN
Doc No: 107261206