23 Jul Biomacromolecule/chitin nanocrystalline composite scaffold material and preparation method thereof
Abstract
The invention discloses a biomacromolecule/chitin nanocrystalline composite scaffold material and a preparation method thereof. Being a blend, the biomacromolecule/chitin nanocrystalline composite scaffold material comprises a biodegradable macromolecule and chitin nanocrystalline in a mass ratio of 1:10-1:100. The biodegradable macromolecule/chitin nanocrystalline composite bone tissue scaffold material is prepared by a freezing/pore-foaming agent leaching method. The composite scaffold has an average porosity of greater than 85%, the pore diameter is regulatable, and the compression modulus is 2MPa-12MPa. By introducing chitin nanocrystalline into a biomacromolecule porous scaffold, the mechanical strength and bioactivity of the scaffold are improved, and the adhesion of cells on the scaffold and the mineralization activity are promoted. The biomacromolecule/chitin nanocrystalline composite scaffold can be applied in the bone repair field as a bone tissue engineering scaffold.
Year: 2014
Country: CN
Doc No: 104001208