Biological 3D printed full-custom skin and preparation method thereof

Biological 3D printed full-custom skin and preparation method thereof

Abstract

The invention relates to the technical field of tissue engineering skin and specifically relates to biological 3D printed full-custom skin and a preparation method thereof. The preparation method comprises two parts of a skin stem cell extraction technology and a skin biological 3D remodeling technology. The skin stem cell extraction comprises the steps: tissue obtaining and treatment, tissue enzymolysis, primary cell culture, subculture and the like. A biological 3D printer is utilized, a three-dimensional scanning modeling technology is utilized, a method of printing raw materials, calculating printing specifications, printing a substrate, printing layer by layer and stacking layer by layer is utilized, full-custom skin completely meeting a specific part and a specific three-dimensionalcharacteristic of the human body can be printed out, complete attachment between artificial skin and wound is ensured, and a transplanting success rate and a healing effect are improved. Meanwhile, the full-custom skin can be applied to research of in-vitro skin models and plays an important role in the aspects of tumor research, medicine, cosmetic testing and the like.

Year:  2018

Country:  CN

Doc No:  108392676

 

For more information visit espacenet.com

Read more