23 Jul Betaine type amphoteric ionic compound modified graphene oxide and preparation method thereof
Abstract
The invention discloses betaine type amphoteric ionic compound modified graphene oxide and a preparation method thereof. The preparation method comprises the steps: firstly, through hydrolysis of a silane coupling agent containing thiol, carrying out sulfhydrylation treatment on the surface of graphene oxide; then, grafting an ethylene carboxylic acid or sulfobetaine type amphoteric ionic compound to the surface of graphene oxide by using a high-efficiency thiol-ene click-on chemical reaction, and thus obtaining the betaine type amphoteric ionic compound modified graphene oxide. The prepared betaine type amphoteric ionic compound modified graphene oxide has excellent biocompatibility, the preparation method is simple and feasible, high in reaction efficiency and selectivity and easy to regulate and control, and the product post-processing is simple and convenient. The method provides a new way for improvement of the biocompatibility of graphene oxide. The betaine type amphoteric ionic compound modified graphene oxide has wide application prospects in the fields of medical devices, tissue engineering scaffolds, drug slow release, anti-bacterial adhesion and other biomedical materials.
Year: 2016
Country: CN
Doc No: 105293478