23 Jul Bacterial cellulose/polyionic liquid antibacterial film and preparation method thereof
Abstract
The invention relates to a bacterial cellulose/polyionic liquid (BC/PIL) antibacterial film and a preparation method thereof. The preparation method comprises the following steps: (1) preparing bacterial cellulose: preparing the bacterial cellulose gel film from cellulose bacterium komagataeibacter rhaeticus TJPU03 screened and produced in a laboratory of inventors through a static culture process; (2) preparing monomers of ionic liquids (ILs): preparing the novel environment-friendly ionic liquids by selecting natural compounds amino acids and choline; and introducing double bonds into the ionic liquids (ILs) under the action of N-hydroxysuccinimide (NHS) and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) through acrylic acid (AAc) to obtain the polymerizable ionic liquid monomers; and (3) preparing the bacterial cellulose/polyionic liquid (BC/PIL) antibacterial film: introducing the ionic liquid monomers into a bacterial cellulose network by using in-situ radical polymerizationto prepare the BC/PIL composite film. The method is simple and fast, the conditions are mild, large-scale equipment is not needed, the water phase reaction is environmentally friendly, and the obtained composite film has good mechanical properties, biocompatibility, biodegradability, drug slow-release function and antibacterial properties, and has broad application prospects in the fields of biological medicine and tissue engineering.
Year: 2020
Country: CN
Doc No: 110917381