23 Jul Artificial uterus three-dimensional gel model used for researching development and differentiation of embryonic stem cells
Abstract
The invention relates to an artificial uterus three-dimensional gel model used for researching development and differentiation of embryonic stem cells, belonging to the research field of tissue engineering and regenerative medicine, and mainly solving the problem that no ideal bionic model exists for the research of differentiation and development of embryonic stem cells in vitro. The in vitro reconstructed tissue engineered uterus is adopted as a research model of the differentiation and development of the embryonic stem cells, wherein the embryonic stem cells are inoculated on the surface or evenly combined inside the uterus lamella, the development environment of normal embryos in vivo is simulated to regulate the microenvironment of the growth and development of the embryonic stem cells, and the reconstructed uterus tissues are taken as the main body to carry out the research on differentiation and development of embryonic stem cells, thus disclosing the inherent law and mechanism of the differentiation and development of embryonic stem cells in vitro, and searching for new methods for directional differentiation of embryonic stem cells to the functional cells of important vital organs at the terminal differentiation period; and the research results have an important meaning to disclose the development of the embryos in the early period, and have important theoretical meaning and application values for the curing based on embryonic stem cells.
Year: 2010
Country: CN
Doc No: 101711891