Antibacterial self-repairing hydrogel and preparation method thereof

Antibacterial self-repairing hydrogel and preparation method thereof

Abstract

The invention relates to an antibacterial self-repairing hydrogel and a preparation method thereof. According to the invention, the hydrogel is endowed with a self-repairing function by a physical crosslinking method based on a hydrophobic effect; the hydrogel is endowed with antibacterial properties and conductivity through introduction of choline-amino acid ionic liquid (VILs); and the tensile property and toughness of the hydrogel are enhanced by bacterial cellulose (BC) with good biocompatibility. The preparation method of the hydrogel comprises the following steps: (1) synthesis of choline-amino acid ionic liquid; (2) preparation of a vinyl choline-amino acid ionic liquid monomer (VILs); (3) purification and hydrolysis of bacterial cellulose; and (4) forming of the polycholine-amino acid ionic liquid self-repairing hydrogel. The hydrogel disclosed by the invention is high in self-healing efficiency, has good antibacterial property, mechanical property, conductivity and biocompatibility, and is applicable to the fields of biology, medical treatment and tissue engineering.

Year:  2020

Country:  CN

Doc No:  110845744

 

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