23 Jul Anatomical composite three-dimensional scaffold tissue engineering cartilage and preparation method thereof
Abstract
The invention relates to an anatomical composite three-dimensional scaffold tissue engineering cartilage and a preparation method thereof. According to the anatomical composite three-dimensional scaffold tissue engineering cartilage, a scaffold is made of polycaprolactone-hydroxyapatite composite material; IGF-1 PLGA microspheres are carried on the scaffold; and the adding amount of the IGF-1 PLGA microspheres is 0.1%-2% of the weigh of the scaffold. The novel three-dimensional porous scaffold prepared by the method has good biocompatibility and biodegradability and is free of cytotoxicity, can be gradually degraded along with regeneration of normal cartilage tissues after being implanted into a living body, and is finally replaced with regenerated cartilage, so that the target of thoroughly healing cartilage injuries is reached.
Year: 2015
Country: CN
Doc No: 104623735