23 Jul Amine compound cross-linking agent and application thereof in hydrogel preparation method
Abstract
The invention provides an amine compound cross-linking agent and an application thereof in a hydrogel preparation method. The amine compound cross-linking agent comprises an amine compound, or is prepared by complexing a plurality of amine compounds. With the amine compound cross-linking agent, through a novel Michael addition crosslinking mechanism, hydrogel is prepared. Through the adjustment upon the ratio of the amine compound, polymer, and solvent, crosslinking density and strength of the hydrogel can be changed, and the swelling performance of the hydrogel can be further influenced. The hydrogel provided by the invention is harmless to bodies, and has no cytotoxicity. The hydrogel can be widely applied in the biomedical field, and can be used in cell culture, tissue engineering, biological activity surface modification, and the like.
Year: 2014
Country: CN
Doc No: 103497355