23 Jul Acetylated modified fibroin/bacterial cellulose composite hydrogel film and preparation method thereof
Abstract
The invention provides an acetylated modified fibroin/bacterial cellulose composite hydrogel film and a preparation method thereof. The specific preparation method comprises the following steps of: adding a fibroin solution into a phosphoric acid buffer solution, dripping methacrylic acid ester while stirring at constant temperature, continuing stirring at constant temperature after dripping, dialyzing after reaction, and freeze drying to obtain acetylated modified fibroin powder; adding the acetylated modified fibroin powder into a fermentation medium of Acetobacter xylinum, standing for fermentation, taking out, and washing to obtain a bacterial cellulose film loaded with the acetylated modified fibroin; placing the bacterial cellulose film loaded with the acetylated modified fibroin inan ultraviolet light environment for curing and crosslinking to obtain the product. The acetylated modified fibroin/bacterial cellulose composite hydrogel film prepared by the invention has obviouslybetter biocompatibility, mechanical strength and biodegradability than existing products, can meet the use requirements of tissue engineering, and has good comprehensive performance.
Year: 2019
Country: CN
Doc No: 110093041