23 Jul A preparing method of injectable hydrogel of a chemically bonded anticancer medicine
Abstract
The invention discloses a preparing method of injectable hydrogel of a chemically bonded anticancer medicine. Hyperbranched polyamide grafted with the anticancer medicine is adopted as a first component, oxidized sodium alginate is adopted as a second component, and the two components adopt formed -C=N- bonds as crosslinking points to obtain the injectable hydrogel capable of sustained release of the anticancer medicine in a body. The traditional Chinese medicine and hydrogel are chemically bonded, thus prolonging the medicine release period. After the hydrogel is degraded, the medicine is still bonded with a macromolecule compound, thus prolonging the circulation time of the medicine in an organism and correspondingly improving treatment effects of the medicine, thereby reducing the medicine taking frequency and relieving toxic and side effects. The injectable hydrogel has a very good application prospect in the field of biological medicines, tissue engineering, and the like.
Year: 2016
Country: CN
Doc No: 105521496