23 Jul A biomimetic composition reinforced by a polyelectrolytic complex of hyaluronic acid and chitosan
Abstract
Provided is a fluid mass composition formed by the process comprising: blending dry hyaluronic acid particles and dry protonated chitosan particles; and adding an aqueous solution to the blend, wherein said fluid mass composition comprises unreacted protonated chitosan hydrogel, unreacted hyaluronic acid viscoelastic gel and polyelectrolytic complex fibers, wherein said polyelectrolytic complex fibers form a three dimensional network throughout the fluid mass composition that surrounds and penetrates the unreacted protonated chitosan hydrogel and the unreacted hyaluronic acid viscoelastic gel and maintains homogeneous regions of the unreacted protonated chitosan hydrogel and the unreacted hyaluronic acid viscoelastic gel. Further provided are tissue engineering materials and biomimetic compositions comprising the said fluid mass composition.
Year: 2009
Country: NZ
Doc No: 548177