23 Jul Hydroxy alkanoic acid polymer and its producing method
Abstract
The present invention discloses one kind of hydroxy alkanoic acid polymer, that is, 3-hydroxy butyric acid-3-hydroxy caprylic acid polymer (PHBHO). The 3-hydroxy butyric acid-3-hydroxy caprylic acid polymer (PHBHO) is prepared with Sinorhizobium fredii as production strain, carbohydrate as carbon source and ammonium salt as nitrogen source, and through high density fermentation and metabolism regulation with lauric acid in optimal culture medium and under optimal culture condition. Corresponding fermentation management method, separation and purification method and quality detection method are established. The present invention can obtain PHBHO product up to 14.4-22.1 g/L, of molecular weight of 112000-185000 Da, and endotoxin content 4-6 EU/g, and the novel nanometer level material may be used in biomedicine and medical tissue engineering.
Year: 2005
Country: CN
Doc No: 1648149