SYSTEM AND METHODS FOR PREFERENTIALLY ENHANCING ACTIVATION OF RAC GTPASE IN A CELL OR TISSUE

SYSTEM AND METHODS FOR PREFERENTIALLY ENHANCING ACTIVATION OF RAC GTPASE IN A CELL OR TISSUE

Abstract

A system and methods for preferentially enhancing activation of Rac GTPase in a cell or tissue is disclosed. Rac activation in the cell or tissue is sustained and does not default to a Rho or Rho kinase regulated pathway. The system and methods of the invention can be used in a variety of in vitro, in vivo, and ex vivo applications including cell culture, tissue culture, tissue engineering, and organ culture.

Year:  2006

Country:  WO

Doc No:  2006094076

 

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