23 Jul PREPARATION AND CHARACTERIZATION OF POLYETHYLENEGLYCOL/POLYESTERS AS BIOCOMPATIBLE THEMO-SENSITIVE MATERIALS
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Abstract
Provided is a biocompatible and temperature-sensitive polyethylene glycol/polyester block copolymer, which shows a phase transition depending on variations in temperature to form a gel with a desired shape in vivo, and is useful as a scaffold for tissue engineering. The biocompatible and temperature-sensitive polyethylene glycol/polyester block copolymer comprises: a hydrophilic segment comprising polyethylene glycol; and a biodegradable polyester-based hydrophobic segment comprising a caprolactone segment, paradioxanone segment, trimethylene carbonate segment or a combination thereof. The polyethylene glycol/polyester block copolymer has a molecular weight of 2,000-7,000 g/mole.
Year: 2007
Country: KR
Doc No: 100668046