23 Jul Arterial vessel tissue engineering reactor simulating physiological pulsating flow surrounding
Abstract
The invention discloses a quasi-physiological pulsatile flow environment arterial blood vessel tissue engineering reactor; the reactor includes a liquid storage bottle, a pulsation source, a resistance regulator, a compliance regulator and a blood vessel tissue dynamic culture cavity and is controlled by an industrial control computer; the reactor overcomes the shortcomings that the commonly used arterial blood vessel tissue engineering reactor in the tissue engineering filed can not simulate the blood flow compliance of the arterial blood vessel, flow inertia, flow resistance and other resistance characteristics and can not provide the quasi blood pulsatile flow environment in the artery; the reactor has the following functions that: a. the reactor is used for culturing the tissue engineering arterial blood vessel; b. the reactor is used for simulating the pulsating frequency, pulse waveform, secondary wave, amplitude and time phase of the pulsatile flow of the different arterial blood vessel under the physiological state, simulating the hemodynamics environment of high vessel inner pressure and high shear stress of the arterial blood vessel under the hypertension and other pathological states and simulating the hemodynamics status of the arterial blood vessel during the low shear stress.
Year: 2008
Country: CN
Doc No: 101245314