23 Jul Weight bearing tissue engineering bone porous pure magnesium bracket and bracket imitation human bone material surface coatings
Abstract
A weight bearing tissue engineering bone porous pure magnesium stent and a surface coating of human bone simulating material of the stent are provided. The stent is made from high pure magnesium powder and pore former into cylinders or round plates with certain diameter (D) and height (H) through powder metallurgy and main holes (1), interlocking pores (2) and blind holes (3) are randomly distributed. The main holes are mutually communicated. The blind holes are enclosed. The total volume of all holes and pores occupies 35-55 percent of the outer contour volume of the stent. The volume of the blind holes occupies 2-5 percent in all holes and pores. The diameter of the main holes and the blind holes is 200-500Mum, and the diameter of communicating holes is 50-100Mum. The formation of the surface coating of the human bone simulating material of the stent (4) is that the stent is immersed in the coating solution with a constant temperature of 37 DEG C, and the coating solution contains Na<+>, K<+>, Ca<2+>, Mg<2+>, HCO3-, Cl<->, HPO4<2->, SO4<2-> and Type I collagen. Finally, the coating of the stent is formed into hydroxyapatite containing magnesium ions and the Type I collagen, and the thickness is 1-3Mum.
Year: 2008
Country: CN
Doc No: 101259293