Tissue engineering scaffold containing alginate, glycosaminoglycan and collagen and preparation method thereof

Tissue engineering scaffold containing alginate, glycosaminoglycan and collagen and preparation method thereof

Abstract

The invention belongs to the tissue engineering scaffold field and particularly provides a tissue engineering scaffold containing alginate, glycosaminoglycan and collagen and a preparation method thereof. The tissue engineering scaffold provided by the invention is prepared by the following raw materials by weight percent: 5-30% of chitosan, 5-30% of collagen, 5-30% of alginate, 0.1-3% of hyaluronic acid, 0.01-0.05% of crosslinking agent, 0.1-3% of chondroitin sulfate, 5-20% of polyvinyl alcohol and the balance tertiary distilled water. For optimization, the tissue engineering scaffold also contains a proper amount of cell growth factor, fibronectin and laminin. The tissue engineering scaffold can be processed and shaped and can be used to prepare products with different forms and thickness, the shaping method is easy to operate, the raw materials are easy to get and not expensive and the tissue engineering scaffold can be used for scale industrialized production.

Year:  2010

Country:  CN

Doc No:  101632841

 

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