23 Jul Nanometer hydroxyapatite/natural polymer composite, preparation method and application thereof
Abstract
The invention relates to tissue engineering materials and particularly discloses a nanometer hydroxyapatite/natural polymer composite, a preparation method and an application thereof. The preparation method includes the steps of putting the natural polymer composite into the mixed solution of alcohol, water and urea and adding monosodium phosphate solution and calcium chloride solution to conduct sealing reaction and obtain the composite, wherein the volume ratio of the alcohol and the water in the mixed solution is 2-6:1, the concentration of urea in the mixed solution is 1-3g/100ml. The method is quick and effective, the conditions of the reaction system are mild, the reaction method and the reaction system are easy to operate and control, the cost is low and investment of high energy source is saved. The composite obtained by the method has a thicker mineralization layer and therefore higher tensile and compressive strength and also can be applied to the field of the tissue engineering materials requiring high mechanical strength, for example the manufacture of bone tissue engineering materials.
Year: 2010
Country: CN
Doc No: 101693774