23 Jul Preparation of collagen-chitosan-laser micropore dermal matrix composite membranes
Abstract
The invention relates to preparation of collagen-chitosan-laser micropore dermal matrix composite membranes. The invention discloses a new application of collagen-chitosan, i.e. constructing collagen-chitosan-laser micropore dermal matrix composite membranes in vitro. The invention also discloses a preparation method of collagen-chitosan-laser micropore dermal matrix composite membranes, comprising the following steps: blending collagen and a chitosan solution according to a certain proportion, injecting into a mould, placing dry laser micropore dermal matrix into the mixed solution, carrying out cooling, drying and vacuum dry heat crosslinking to form the collagen-chitosan-laser micropore dermal matrix composite membranes, and irradiating with <60> Co and sterilizing for standby application. The invention provides novel biological support materials for skin tissue engineering; the biological support materials possess certain mechanical strength, favorable biocompatibility and no immunogenicity; the raw materials are wide and easy to obtain; and the preparation is easy.
Year: 2010
Country: CN
Doc No: 101856516